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Colorectal Oncology Research Review, Issue 47

Colorectal Oncology Research Review, Issue 47

In this issue:

Survival benefit to adjuvant celecoxib in PIK3CA-mutated colon cancer
High response rates to neoadjuvant immunotherapy in localised dMMR colon cancer
Sotorasib–panitumumab promising for chemo-refractory KRAS G12C-mutated mCRC
Anti-PD-1, HDAC inhibitor and anti- VEGF for MSS/pMMR mCRC
Negative hyperselection using ctDNA may inform front-line use of anti-EGFR
Features of microsatellite instability in pMMR CRC
SCARCE: no benefit to atezolizumab + chemo in anal cancer
Nivolumab + relatlimab beneficial in previously treated MSI-H/dMMR mCRC
Immunoscore prognostic for DFS in stage 3 CRC
Primary tumour resection vs chemotherapy for CRC with unresectable metastases

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Dr-Matthew-Burge

Expert contributor

Dr Matthew Burge

Dr Matthew Burge, is a medical oncologist and staff specialist at the Royal Brisbane Hospital and a visiting specialist at the Rockhampton Base Hospital. He undertook his undergraduate training in Manchester, UK before moving to Australia in 1996. After obtaining his FRACP in 2004 he moved back to the UK to undertake a clinical fellowship […]

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